Full texts provided here are for internal research and educational purposes only. For questions, please contact Dr. Vankee Lin.


† equal contribution


Lin FV. 2022. A multi-dimensional model of fatigue in old age: Implications for brain aging. American Journal of Geriatric Psychiatry.

*Turnbull A, Anthony M, Tadin D, Porsteinsson A, Heffner K, Lin F. 2022. Effect of online tDCS to left somatomotor cortex on neuropsychiatric symptoms among older adults at risk for dementia. Cortex

Turnbull A, Seitz A, Tadin D, Lin FV. 2022. Unifying framework for cognitive training interventions in brain aging. Ageing Research ReviewsPDF

Turnbull A, Kaplan R, Adeli E, Lin FV. 2022. A Novel Explainability Approach for Technology-Driven Translational Research on Brain Aging. Journal of Alzheimer's Disease.

*Chen Q, Turnbull A, Cole M, Zhang Z, Lin F. 2022. Enhancing Cortical Network-level Participation Coefficient as a Potential Mechanism for Transfer in Cognitive Training in aMCI. NeuroImagePDF


*Baran T, Lin F, Geha P. 2021. Functional brain mapping in patients with chronic back pain shows age-related differences. PainPDF

*†Turnbull A, Poerio GL, Ho NSP, Martinon LM, RIby LM, Lin FV, Jefferies E, Smallwood J. 2021. Age-related changes in ongoing thought relate to external context and individual cognitionConsciousness and Cognition. PDF

Lin F, Heffner K, Gevirtz R, Zhang Z, Tadin D, Porsteinsson A. 2021. Targeting Autonomic Flexibility to Enhance Cognitive Training Outcomes in Older Adults with Mild Cognitive Impairment: Study Protocol for a Randomized Controlled Trial. Trials.

*Heffner KL, Quiñones MM, Gallegos AM, Crean HF, Lin F & Suhr JA. 2021. Subjective memory in adults over 50 years of age: Associations with affective and physiological markers of emotion regulation. Aging & Mental Health

*Kukla B, Anthony M, Chen S, Turnbull A, Baran TM, Lin F. 2021. Brain Small-Worldness Properties and Perceived Fatigue in Mild Cognitive Impairment. The Journal of Gerontology: Series A. PDF

*Chen Q, Baran TM, Turnbull A, Zhang Z, Rebok GW, Lin F. 2021. Increased Segregation of Structural Brain Networks Underpins Enhanced Broad Cognitive Abilities of Cognitive Training. Human Brain Mapping. PDF


*Chen Q, Turnbull A, Baran TM, Lin F. 2020. Longitudinal stability of medial temporal lobe connectivity is associated with tau-related memory decline. eLife. PDF

*Wang L, Lin F, Cole M, Zhang Z. 2020. Learning Clique Subgraphs in Structural Brain Network Classification with Application to Crystalized Cognition. Neuroimage. PDF

*Anderson A, Heffner K, Dodell-Feder D, Lin, F. 2020. Decoding individual identity from brain activity elicited during the recollection of personal experiences. Nature Communications.​​ PDF

*Chen Q, Baran, TM, Rooks, B, O’Banion, MK, Mapston, M., Zhang, Z, Lin, F. 2020. Cognitively supernormal older adults maintain a unique structural connectome that is resistant to Alzheimer's pathology. NeuroImage: Clinical. PDF


*Lin F, Cottone K, McDermott K, Jacobs A, Nelson D, Porsteinsson A, Chapman B. 2020. Attitudes toward computers moderate the effect of computerized cognitive trainings in oldest-old senior living center residents. American Journal of Geriatric Psychiatry. PDF

*Chen Q†, Yang H†, Rooks B, Anthony M, Zhang Z, Tadin D & Heffner K, Lin F. 2020. Autonomic flexibility reflects learning and associated neuroplasticity in old age. Human Brain Mapping. PDF


*Lin F, Tao Y, Chen Q, Anthony M, Zhang Z, Tadin D & Heffner K. 2020. Processing speed and attention training modifies autonomic flexibility: A mechanistic intervention study. NeuroImagePDF


*Rooks B†, Anthony M†, Chen Q, Lin Y, Baran T, Zhang Z, Lichtenberg P & Lin F. 2019. A generic brain connectome map linked to different types of everyday decision-making in old age. Brain Structure and Function. PDF

*Anderson AJ, Binder J, Fernandino L, Humphries C, Conant L, Raizada R, Lin F† & Lalor E†. 2019. An integrated neural decoder of linguistic and experiential meaning. Journal of NeurosciencePDF

*Baran T, Zhang Z, Anderson AJ, McDermott K & Lin F. 2019. Brain structural connectomes indicate shared neural circuitry involved in subjective experience of cognitive and physical fatigue. Brain Imaging BehavPDF

*Wang X, Heffner K, Anthony M & Li F. 2019. Stress adaptation in older adults with and without cognitive impairment: an fMRI pattern-based similarity analysis. Aging. PDF

*Anderson AJ, Ren P, Baran T, Zhang Z & Lin F. 2019. Insula and putamen centered functional connectivity networks reflect healthy agers’ subjective experience of cognitive fatigue in multiple tasks. Cortex. PDF


*Ren P, Anderson AJ, McDermott K, Baran T & Lin F. 2019. Cognitive fatigue and cortical-striatal network in old age. Aging. PDF

*McDermott K†, Ren P†, Lin F. 2019. The mediating role of hippocampal networks on stress regulation in amnestic mild cognitive impairment. Neurobiology of Stress. PDF

Anderson AJ & Lin F. 2019. How pattern information analyses of semantic brain activity elicited in language comprehension could contribute to the early identification of Alzheimer’s Disease. Neuroimage: Clinical. PDF

†Yu F, †Lin FV, Salisbury DL, Shah KN, Chow L, Vock D, Nelson NW, Porsteinsson AP, Jack C Jr. 2019. Efficacy and mechanisms of combined aerobic exercise and cognitive training in mild cognitive impairment: study protocol of the ACT trial. TrialPDF


*Baran T & Lin F. 2018. Amyloid and FDG PET of successful cognitive aging: Global and cingulate-specific differences. Journal of Alzheimer’s DiseasePDF

*Ren P, Chapman B, Zhang Z, Schifitto G & Lin F. 2018. Functional and structural connectivity of the amygdala underpins locus of control in mild cognitive impairment. Neuroimage: Clinical. PDF

*Anderson A, Lalor E, Lin F, Binder J, Fernandino L, Humphries C, Conant L, Raizada R, Grimm S & Wang X. 2018. Multiple regions of a cortical network commonly encode the meaning of words in multiple grammatical positions of read sentences. Cerebral Cortex. PDF

*Yu F, Chen Y, Mathiason MA, Wan Q & Lin F. 2018. Cognitive and physical factors affecting daily function in Alzheimer's disease: A cross-sectional analysis. Nursing & Health Sciences

Anthony M & Lin F. 2018. A systematic review for functional neuroimaging studies of cognitive reserve across the cognitive aging spectrum. Archives of Clinical NeuropsychologyPDF

*Wang X, Ren P, Baran T, Raizada R, Mapstone M & Lin F. 2018. Longitudinal functional brain mapping in Supernormals. Cerebral CortexPDF


*Lin F, Ren P, Wang X, Tadin D, Heffner K. 2017. Cortical thickness is associated with altered autonomic function in cognitively impaired and non-impaired older adults. Journal of PhysiologyPDF

*†Wang X, †Ren P, Mapstone M, Conwell Y, Porsteinsson A, Foxe J, Raizada R, Lin F. 2017. Identify a shared neural circuit linking multiple neuropsychiatric symptoms with Alzheimer’s pathology. Brain, Imaging and BehaviorPDF

*Ren P, Heffner K, Jacobs A, Lin F. 2017. Acute affective reactivity and quality of life in older adults with amnestic mild cognitive impairment: A functional MRI study. The American Journal of Geriatric PsychiatryPDF

*Chapman B, Benedict C, Lin F, Roy S, Porsteinsson P, Szigeti K, Federoff H, Mapstone M. 2017. Apolipoprotein E genotype impact on memory and attention in older persons: the moderating role of personality phenotype. International Journal of Geriatric Psychiatry. PDF

*Lin F, Wang X, Wu R, Rebok G, Chapman B. 2017. Identification of successful cognitive aging in the Alzheimer’s Disease Neuroimaging Initiative Study. Journal of Alzheimer’s DiseasePDF


Victoroff J, Lin F, Coburn K, Shillcutt S, Voon V, Ducharme S. 2017. Noncognitive behavioral changes associated with Alzheimer's disease: Implications of Neuroimaging Findings. Journal of Neuropsychiatry and Clinical Neurosciences. PDF


*Ren, P, Anthony M, Heffner K, Chapman B, Lin F. 2017. Amygdala functional connectivity is associated with locus of control in the context of cognitive aging. NeuropsychologiaPDF

*Chapman B, Benedict R, Lin F, Roy S, Federoff H, Mapstone M. 2017. Personality and performance in specific neurocognitive domains among older persons. The American Journal of Geriatric Psychiatry. PDF

*Lin F, Heffner K, Ren P, Tadin D. 2017. A role of the parasympathetic nervous system in cognitive training. Current Alzheimer’s ResearchPDF

*†Shah K, †Lin F, Yu F, McMahon J. 2017. Activity engagement and physical function in old age sample. Archives of Gerontology and GeriatricsPDF

*Mapstone M, Lin F, Nalls M, Cheema A, Singleton AB, Fiandaca M, Federoff H. 2017. What success can teach us about failure: the plasma metabolome of older adults with superior memory and lessons for Alzheimer's disease. Neurobiology of AgingPDF

*Lin F, Ren P, Mapstone M, Meyers S, Porsteinsson A & Baran T. 2017. The cingulate cortex of older adults with excellent memory capacity. CortexPDF

*Lin F, Ren P, Lo Y, Chapman B, Jacobs A, Baran T, Porsteinsson A & Foxe J.  2017. Insula and inferior frontal gyrus' activations protect memory performance against Alzheimer's pathology in old age. Journal of Alzheimer’s DiseasePDF


Wu R, Rebok G & Lin F. 2016. A novel theoretical life course framework for triggering cognitive development across the lifespan. Human DevelopmentPDF

*Ren P, Lo R, Chapman B, Mapstone M, Porsteinsson A & Lin F. 2016. Longitudinal alteration of intrinsic brain activity in the striatum in mild cognitive impairment. Journal of Alzheimer’s DiseasePDF

*Lin F, Ren P, Cotton K, Porsteinsson A, Mapstone M & Heffner K. 2016. Mental fatigability and heart rate variability in mild cognitive impairment. The American Journal of Geriatric Psychiatry. PDF


*Lin F, Heffner K, Ren P, Tivarus M, Brasch J, Chen D, Mapstone M, Porsteinsson A & Tadin D. 2016. Cognitive and neural effects of vision-based speed of processing training in older adults with amnestic mild cognitive impairment: A pilot study. Journal of the American Geriatrics SocietyPDF


*David ND†, Lin F† & Porsteinsson A. 2016. Trajectories of neuropsychiatric symptoms and cognitive decline in mild cognitive impairment. The American Journal of Geriatric Psychiatry. PDF

< 2015

*Hill N, Mogle J, Colancecco E, Dick R. Hannan J, Lin F. 2015. Feasibility study of an attention training application for older adults.  International Journal of Older People Nursing.

*†Lin F, †Roiland R, Chen DG, Qiu C. 2015. Linking cognition and frailty in middle and old age: Metabolic syndrome matters. International Journal of Geriatric Psychiatry. PDF

*†Roiland R, †Lin F, Phelan C, Chapman B. 2014. Stress regulation as a mechanism linking executive function and pre-frailty. Journal of Nutrition, Health, and Aging. PDF

Chen DG, Chen X, Lin F, Tang WYL, Guo Y. 2014. Cusp catastrophe polynomial model: power and sample size determination. Open Journal of Statistics. PDF

*†Lin F, †Lo R, Cole D, Ducharme S, Mapstone M, Porsteinsson A, ADNI Group. 2014. Longitudinal effects of metabolic syndrome on Alzheimer and vascular related brain pathology. Dementia and Geriatric Cognitive Disorders Extra. PDF

*Lin F, Roiland R, Heffner K, Johnson M, Chen DG, Mapstone M. 2014. Evaluation of objective and perceived mental fatigability in older adults with vascular risk. Journal of Psychosomatic Research. PDF

Chen DG, Chen C, Tang W, Lin F. 2014. Statistical power analysis for Guastello's cusp catastrophe polynomial regression model: A simulation-based approach. Lecture in W.G. Kennedy, N. Agarwal, and SJ. Yang (Eds.): SBP 2014, Lecture Notes in Computer Science 8393, pp, 35-41.


*Lin F, Suhr J, Diebold S, Heffner K. 2014. Associations between depressive symptoms and memory deficits vary as a function of insulin-like growth factor (IGF-1) levels in healthy older adults. Psychoneuroendocrinology. PDF

*†Chen DG, †Lin F, Chen X, Wang T, Kitzman H. 2014. Cusp catastrophe model: A nonlinear model for health outcomes in nursing research. Nursing Research. PDF

*Lin F, Roiland R, Polesskaya O, Chapman B, Johnson M, Brasch J, Chen D, Mapstone M. 2014. Fatigability disrupts cognitive processes' regulation of inflammatory reactivity in old age. The American Journal of Geriatric Psychiatry. PDF

Johnson M, Lin F. 2014. Communication difficulty and relevant interventions in Mild Cognitive Impairment. Topics in Geriatric Rehabilitation. PDF


*Lin F, Heffner KL, Mapstone M, Chen D, Porsteinsson AP. 2014. Frequency of mentally stimulating activities modifies the relationship between cardiovascular reactivity and executive function in old age. The American Journal of Geriatric Psychiatry. PDF

*Lin F, Chen D, Vance DE, Ball K, Mapstone M. 2013. Longitudinal relationships of subjective fatigue, cognitive function, and everyday functioning in old age. International Psychogeriatrics. PDF


*Lin F, Chen D, Vance DE, Mapstone M. 2013. Trajectories of combined laboratory- and real world-based speed of processing in community-dwelling older adults: Predictors and functional outcomes. Journal of Gerontology Series B: Psychological Sciences and Social Sciences. PDF

Lin F, Vance DE, Gleason CE, Heidrich SM. 2012. Taking care of older adults with mild cognitive impairment: An update for nurses. Journal of Gerontological Nursing. PDF

*Lin F, Friedman E, Quinn J, Chen D, Mapstone M. 2012. Effect of leisure activities on inflammation and cognitive function in an aging sample. Archives of Gerontology and Geriatrics. PDF

*Lin F, Heidrich SM. 2012. Role of older adult’s illness schemata in coping with mild cognitive impairment. Journal of Psychosomatic Research. PDF

Vance DE, Kaur J, Fazeli PL, Talley MH, Yuen HK, Lin F. 2012. Neuroplasticity and successful cognitive aging: A brief overview for nursing. Journal of Neuroscience Nursing. PDF

*Lin F, Gleason CE, Heidrich SM. 2012. Illness representations in older adults with mild cognitive impairment. Research in Gerontological Nursing. PDF

*Lin F, Wharton W, Dowling NM, Ries ML, Johnson SC, Carlsson CM, Asthana S, Gleason CE. 2010. Awareness of memory abilities in community-dwelling older adults with suspected dementia and mild cognitive impairment. Dementia and Geriatric Cognitive Disorders. PDF